Seconding this.  I'm not certain that this is something you'd be interested in, but if you are that would be great.  I'm particularly interested in illnesses--they're one of the things from TS2 that I miss the most (except it would be nice if they would last longer and have more obvious symptoms than in TS2).  Someone posted about the possibility of doing this on nraas a while back (http://nraas.wikispaces.com/message/view/Chatterbox/54750322?o=0), but the person was not experienced with modding and nothing came of it (unsurprisingly).

I'd also like to echo the request for something to allow pregnancies without woohoo/using random sperm donations.