http://forums.sims2community.com/showthread.php?t=27344 there's a pretty comprehensive list on Sims 2 Community forums of what does and doesn't work.  The inTeen is out though that's not much of a surprise.  So is Squinge pregnant Sims wear everyday  

  That makes me not even want to install the ep...
I would go there.  Apparently all custom careers, majors and foods don't work.  But I still have my custom careers in the game and it's been fine, everything else from the list, I removed.